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Not only do these minerals make up a small portion of bile but they also are needed for processes like active transport of bile acids and the adequate opening and closing of valves associated with biliary output.* Unfortunately in the modern diet (especially if were coming from a processed lifestyle) electrolytes are typically out of balance

Mitochondrial dysfunction and oxidative stress: a vicious cycle In ME/CFS, elevated ROS and RNS levels are associated with mitochondrial dysfunction by damaging mtDNA and membranes, disrupting the ETC, and triggering mitophagy

NNMT (nicotinamide N-methyltransferase) and NAD+ (nicotinamide adenine dinucleotide) are related but distinct in their individual roles and functions within the body

(3) measuring the separation time of RBCs and plasma in a whole blood sample during centrifugation

doi: 10.3389/fonc.2025.1700439 Received 11 September 2025 Accepted 27 October 2025 Published 17 November 2025 Volume 15 - 2025 Edited by Zodwa Dlamini, Pan African Cancer Research Institute (PACRI), South Africa Reviewed by Yuan Qin, Xijing Hospital, The Air Force Medical University, China Hong Sun, Fudan University, China Updates Copyright 2025 Ao, Liu, Yin and Zhao