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Animal studies have demonstrated that the NaIO 3 -induced AMD model has ferroptosis-related characteristics

70 The reads alignment and gene models were based on Mus_musculus.GRCm39.107.gtf.gz

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To understand the catalytic mechanism of the ADP-ribosylhydrolase (ARH) activity of MavL, we screened its active truncation mutants and succeeded in solving the structure of the MavL 40-404 -ADPR complex at a resolution of 2.38 , which revealed that several pairs of hydrogen bonds and a - stacking interaction provided by surrounding amino acids or water molecules are involved in interactions between MavL and ADPR (Supplementary Fig