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Run a compound indefinitely with no reference point and you cant separate this is working from Ive convinced myself its working. Breaks keep the assessment honest

In this study, we demonstrated that exogenous cystine enhanced the bactericidal effect of gentamicin against drug-resistant Salmonella by activating the glutathione pathway while decreasing GSH/GSSG, thereby disrupting cellular redox homeostasis, increasing ROS production, and activating the Fenton reaction

[PMC free article: PMC2836043] [PubMed: 20018878] 793

In addition, NOX-2 produces ROS during respiratory burst

J Neurooncol (2010) 99:2532.10.1007/s11060-009-0107-y 25 ShimazuSShimatsuAYamadaSInoshitaNNagamuraYUsuiTet alResistance to dopamine agonists in prolactinoma is correlated with reduction of dopamine D2 receptor long isoform mRNA levels