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Sleep deprivation can cause an imbalance in certain hormones, like cortisol (one of the stress hormones mentioned earlier)

doi: 10.1016/j.addr.2015.07.007 272 Martinez-OutschoornUEBallietRMRivadeneiraDBChiavarinaBPavlidesSWangCet al

Rouhier, N

First, GSH is vital for normal cellular functions, including detoxification and protection against oxidative stress, so systemic depletion can damage healthy tissues such as the liver, kidneys, and bone marrow