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Extensive research has established glutathione peroxidase 4 (GPX4) as a critical regulator in the pathogenesis of multiple pathological conditions, including osteoarthritis 35 ,cancers 47 , and liver disease 48

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doi:10.3109/13590849208997961

In parallel, certain plants and herb-based products rich in polyphenols when consumed with medications, require careful monitoring due to potential interactions