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The Sap (sensitivity to antimicrobial peptide) inner membrane ATP-binding-cassette (ABC) transport complex also appears to be important in the ability of NTHi to acquire haem-iron and colonise the host (Mason et al., 2011)

What stands out is not just that these studies met their endpoints, but that many of them changed the question being asked from does it work? to how fast should this become standard? This level of impact signals a healthier, more productive late-stage pipeline and a clearer connection between innovation and patient benefit

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