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These are some serious effects not to be laughed off

Similarly, initial reports of a selective Y4-receptor agonist (TM30339) currently under development were also quite promising inducing reduction of food intake and promoting weight loss

This is in line with the findings of Nemet et al., (2020), who reported PAGln as a gut-derived, phenylalanine-based metabolite with pro-thrombotic effects via adrenergic receptor signaling (Nemet et al., 2020)