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The headline figures by dose group: For context, semaglutides STEP 1 phase 3 trial reported approximately 14.9 percent average weight loss

PLoS One 7(2):e31087, 2012

doi: 10.1016/j.bbadis.2025.168028 Summary Keywords atherosclerosis, ferroptosis, heme oxygenase-1, oxidative stress, ROS Citation Xu J, Chen C, Yuan H-Y, Zhang Y-Y, Wang C-R, Xi X, Pan H, Li D-H and Lu Y (2026) Reappraising heme oxygenase-1 as a ferroptosis modulator in atherosclerosis: a mechanism-focused review