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Oxidized lipid clusters in membranes destroy their barrier function by formation of hydrophilic pores, leading to ferroptosis ( Polyunsaturated fatty acid (PUFA)-containing membranes are susceptible to oxidation ( Figure 3 )

Br J Pharmacol 151:979986 Tiganis T (2011) Reactive oxygen species and insulin resistance: the good, the bad and the ugly

However, the use of random fasting samples and the determination of vitamin B6 expressed as per gram creatinine have been also reported (196)

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