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While additional studies are needed to determine whether elevated vitamin B 12 status may be related to cancer development, including evaluating whether it might be a potential marker of cancer, it is important for observational studies to adequately control for potential confounders, such as age, menopausal status, alcohol use, and intake of the B-vitamin folate

Fix: Store in refrigerator, protect from light, use within 4-6 weeks of reconstitution

Thus suggesting a specificity for IGF-1R

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The nausea typically emerges within 1-2 days of injection and resolves within 48-72 hours