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Similarly, exposure of these mice with Brca1 -associated breast cancer to the topoisomerase I inhibitor topotecan resulted in drug resistance caused by reduced levels of the topoisomerase I drug target and increased expression of the Abcg2 drug efflux pump rather than changes in markers of apoptosis (Zander et al, 2010)

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Learn about Hyperbaric Oxygen Therapy (HBOT) as a potential treatment for Lyme disease, from its effectiveness, risks, and current research findings

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