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Ruxolitinib cream: Ruxolitinib (Opzelura) is a Janus kinase inhibitor (JAK inhibitor) that was approved by theFood and Drug Administration (FDA)for the treatment of non-segmental vitiligo (vitiligo that appears in patches) in adults and children ages 12 years and older

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One thing that could cause this decline is a decrease in blood flow through your body, a process called intermittent claudication