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[90] found a significant increase in alprazolam exposure (2.48-fold in AUC) in ten healthy volunteers concomitantly receiving ritonavir, leading to augmented sedation and performance impairment

The combination preserves physiological feedback loops and receptor cycling

MSCs inhibit pro-inflammatory cytokines (TNF-, IL-6, IL-17) and enhance T-regulatory cell activity, mitigating autoimmune factors associated with POF (Wu et al