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Glutathione peroxidase 4(GPX4), serves as the central enzyme that halts lipid peroxidation and inhibits ferroptosis

However, if the average annual temperature continues to rise at the current rate, even these leading cotton-producing countries will face production losses (Meyer and Dew, 2021)

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In fact, there is an added layer of complexity in how S-nitrosation controls cellular responses, as some proteins are S-nitrosated basally, and loss of this modification (hypo-nitrosation) results in pathologic effects whereas other are not S-nitrosated to begin with and modification of critical thiols (hyper-nitrosation) has deleterious results