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Moreover, the absence of GM-CSF signaling results in type I IFN-induced neutrophil extracellular trap formation that aggravates lung mycobacterial burden and lung pathology (206)

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Main pathway: G-actin sequestration Native T4 binds monomeric G-actin with a dissociation constant (KD) of approximately 1 M, controlling the pool of free actin available for polymerization into F-actin (actin filaments)