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Annals of Hematol:A114, 1991

This suggests that ferroptosis plays a crucial role in explaining the interplay between iron overload, oxidative stress, and selective dopaminergic neuron loss in PD, reinforcing its relevance in PD pathogenesis ( Figure 5 )

Furthermore, it has been reported that the crosstalk between midbrain DA neurons and astrocytes is regulated by the Frizzled-1/-catenin signaling pathway, modulated by WNT1 [135]