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Common signs and symptoms include: Fatigue and weakness Paleness Shortness of breath Dizziness or lightheadedness Tingling or numbness in the hands and feet Difficulty walking or balance problems Memory problems or confusion Mood changes, such as depression or irritability Glossitis (inflammation of the tongue) Mouth ulcers Changes in vision If left untreated, vitamin B12 deficiency can lead to more severe complications, including nerve damage, neurological problems, and anemia

Often, the diarrhea is normal or increased in volume with a normal to slight increase in frequency (2-4 times per day)

19-22 Patients meeting criteria for acute severe UC should be referred urgently for hospital admission and treatment with intravenous corticosteroids

10.1016/j.jbiomech.2019.109573 294 UrbanJ

Independently of GH level, serum concentration of IGF-1 is affected by nutritional status