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Second, aNDBs consist of positively charged molecules (chondroitin sulfate, o-pullulan, alginate, -polylysine, chitosan, magainin-2, etc.), containing cationic groups such as quaternary ammonium, quaternary phosphonium, guanidinium, or tertiary sulfonium (Santos et al., 2016), which have a positive charge

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By increasing the activity of antioxidant enzymes such as glutathione peroxidases and thioredoxin reductases, selenium limits the excessive accumulation of ROS, thus inhibiting the overactivation of this pathway