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Each additional amino acid residue requires an additional coupling step in solid-phase synthesis, adding reagent cost and cumulative yield loss

Sororin-CTR directly binds the closed RAD21-SMC3 interface To elucidate the molecular basis of Sororin-CTR-mediated cohesion stabilization, we examined its interaction with the cohesin complex

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Liver Disease: Severe liver disease or impaired liver function is a contraindication to the use of Diane-35 due to its potential hepatotoxic effects

The choice of nucleic acid starting material, clone of interest, or library type is believed to be a matter of routine for a person of ordinary skill in the art with knowledge of the embodiments described herein