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Moreover, these pathological mechanisms are not independent and can affect each other, thus we summarized these pathological mechanisms in a conceptual figure (Figure 2)

The data were presented as the fold increase of the target gene expression, normalized to the housekeeping gene beta-actin, compared to unstimulated conditions

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Figure 4A illustrates the experimental setup, where 5 10 3 luc-Molm13 cells were injected into NSG mice via tail vein