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Host cells contain pattern recognition receptors (PRRs) which recognize bacterial pathogen-associated molecular patterns (PAMPs)

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Figure 2 presents a timeline of GLP- 1 discovery and clinical development

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Physical symptoms usually include: Headaches or a feeling of pressure in the head Dizziness, balance problems, or fatigue Nausea or repeated vomiting Blurred or double vision Sensitivity to light or noise Changes in sleep patterns Cognitive and thinking changes may include: Confusion or disorientation Trouble concentrating, remembering, or thinking clearly Feeling slowed down or groggy Loss of consciousness for a few seconds to hours Sensory and perception signs: Ringing in the ears (tinnitus) Blurred vision or changes in vision Unusual tastes or loss of smell or taste Emotional and behavioral symptoms may include the following: Irritability or mood swings Restlessness or unusual behavior Anxiety, sadness, or depression Infants and young children may not be able to describe how they feel