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[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Posada A.C., Kolar S.L., Dusi R.G., Francois P., Roberts A.A., Hamilton C.J., Liu G.Y., Cheung A

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The 2025 Zdrada-Nowak review in International Journal of Molecular Sciences confirmed the clinical evidence for AH-8 in wrinkle reduction, elasticity, and hydration, but flagged the specific limitation that low intrinsic skin penetration is the main efficacy ceiling for topical use [12]