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doi: 10.1007/s11064-022-03726-6 58

Int J Mol Sci 22:5313

(2016) was based on the use of carbodiimide chemistry to conjugate a poly(N-vinylpyrrolidone) nanoscaffold to insulin: the obtained nanosystems were protected by protease degradation and capable to link to insulin receptors, trigger insulin signaling and promote neuroprotection effects against the dysfunction induced by amyloid-