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MT-1 and 2 have ubiquitous tissue distribution particularly in liver, pancreas, intestine, and kidney, whereas MT-3 is found in brain and MT-4 in skin [177]

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Clinical impact of switching from subcutaneous apomorphine to foslevodopa/foscarbidopa in advanced Parkinsons disease: a realworld observational study (FOSAPO)

The 12/15-LOX pathway, on the contrary, is activated in microglia when the maternal diet is deficient in omega-3 PUFAs, leading to an overproduction of omega-6 PUFA derivatives such as 12-HETE