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Further development of TGR-based therapeutic approaches is impeded by the lack of non-covalent small molecule inhibitors of TGR, a well-known and general problem for all the members of the high molecular weight, Sec-containing TrxR subfamily that are considered attractive and unexploited drug targets for several human diseases 21,22

The inhibition was specific for mitophagy because neither macro- nor micro-ATG was altered

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Jan 11, 2024, 7:47:44 PM How to choose between affinity tags for protein purification By Rico Duncan Finding the right affinity tag can be a challenging task for many