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Introduction Free copper accumulation in many tissues (liver, brain, cornea, joints) also known as hepatolenticular degeneration mutation in ATP7B results in free copper generates free radicals that damage tissues see Metabolism of copper topic AR inheritance Presentation Symptoms Parkinson-like symptoms hemiballismus dementia Physical exam cirrhosis corneal deposits on slit lamp examination Evaluation total serum copper serum non-ceruloplasmin bound copper urine/serum free copper hemolytic anemia Liver Biopsy If performed will show increased hepatic copper Treatment Medical ammonium tetrathiomolybdate trientine zinc Surgical Consider liver transplantation as clinical condition deteriorates Prognosis, Prevention, and Complications At risk for liver disease hepatitis cirrhosis carcinoma (hepatocellular) Also at risk for Fanconi's disease of the proximal tubules

We work with you one on one where some clinics use the group approach. We want to make sure you feel comfortable and we like to focus our attention on one patient at a time

Antioxidant effectiveness of coffee extracts and selected constituents in cell-free systems and human colon cell lines

C., van der Hoeven, L

For example, if you have a favorite relaxation technique or other stress-reduction strategy, consider putting it to use