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Another advantage of this method is that the amide linkages formed by this technique (as well as those created by the NHS method) are more stable than the isourea linkages obtained by CNBr immobilization

8 The four approved inactivated vaccines were developed by Wuhan Institute of Biological Products (Wuhan, China), Beijing Institute of Biological Products (Beijing, China), Sinovac (Beijing, China) and Bharat Biotech (Hyderabad, India), respectively

(PubMed) Wang K, Yu J, Liu H, et al