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Description

Nifedipine has an increased bioavailability when formulated into cyclodextrins which allows for a faster absorption [218]

Shaking creates mechanical stress and shearing forces that can break the fragile peptide bonds, rendering it useless

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In the TRIUMPH-4 Phase 3 trial, the most common adverse events for the 12 mg dose were nausea (43.2%), diarrhea (33.1%), constipation (25.0%), vomiting (20.9%), and decreased appetite