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10.1038/s41467-017-01191-2 13 AlpatovR.LeschB

Introduction Reactive oxygen and nitrogen species are generated by endogenous and exogenous processes, while enzymatic and non-enzymatic antioxidants neutralize them

These ballistic threats on cities around Ukraine have been escalating over the summer and show no signs of slowing down. Ukrainian attacks on Russia At the same time, in Russias Kirov region on Friday, six people were killed and 26 injured in a Ukrainian missile attack on a factory, the regional governor, Alexander Sokolov, said

Surprisingly, extensive down-regulation of miRNAs such as miR-27a, miR-34a, miR-142-5p, and miR-7, involved in cytoprotection against OS and some of them also capable of targeting Nrf2 directly, has been detected in the muscle, CSF, MN progenitors, and blood as well as in post mortem specimens (brain, brain stem, and the spinal cord) of both sALS and fALS patients, unlike healthy controls [258,259,260,261,262]

For data involving more than one variable, two-way ANOVA with Bonferronis post hoc tests was applied for multiple group comparisons