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This tight, self-regulating loop part of the broader gamma-glutamyl cycle first mapped in detail by Alton Meisters laboratory is the single most important fact to understand before evaluating supplement claims, because it means the body defends a set-point rather than passively accumulating whatever glutathione is swallowed

Which also provoked a review of the relationship between ferroptosis mechanisms and immune system activation [217]

But it can also be a nasty enemy with photoaging, hyperpigmentation, and skin barrier damage

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