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IGF-1 (Insulin-like Growth Factor 1) IGF-1 is an anabolic growth factor that mediates many of the downstream effects of growth hormone

It has also been observed in vitro that SCs and neurites prefer to travel towards softer stiffness substrates 35,36 , suggesting that materials within the lumen which are stiffer than the surrounding tissues can be inhibitory to nerve growth

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BPC-157 focuses on tendon and gut healing

Week 1-2: Adjustment period What happens: Skin adapts to retinol (may see some peeling, redness) Peptides begin signaling collagen production Texture may worsen before improving (retinol purge) What to do: Stick with routine unless severe irritation Reduce retinol frequency if needed Increase moisturizer Week 4-6: Initial improvements What you'll notice: Smoother skin texture Reduced breakouts (if acne-prone) More even tone Skin feels firmer Less irritation as skin adjusts Peptide + retinol advantage: Smoother, more hydrated texture than retinol alone