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Finally, pairwise PLS-DA model saline-alcohol vs caffeine-alcohol (CER = 0.36) also revealed that caffeine was responsible for increased abundance of indole amino acids, phenylalanine, tryptophan, and tyrosine, 6-oxopurine, niacinamide/nicotinamide and arachidonoyl thio-PC, while it decreased the abundance of histidine, acetyl-arginine, acetyl-carnitine, 13-docosenamide, and some PCs, such as stearoyl-myristoyl- and octadecanoyl- glycero-phosphocholine (Supplementary Table 6)

Key highlights Semaglutide with vitamin B12 is an emerging approach to weight loss that may help individuals counteract the side effects of semaglutide, such as fatigue and low energy levels

Liu C, Zhang L, Zhu W, Guo R, Sun H, Chen X, et al

169 Rafati M, Ghasemi A, Saeedi M, et al

Adaptive immune cells Th1 and Th17 cells secrete proinflammatory cytokines such as IFN-, TNF-, and IL-17, which facilitate M1 macrophage polarization, leading to tissue damage repair [146]