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2003;8:d26478

Anxiolytic & Sleep Architecture Peptides Selank is a synthetic heptapeptide analogue of the immunomodulatory tetrapeptide tuftsin, developed in Russia and studied for anxiolytic, nootropic, and neurotrophic effects

Instead, the researchers found that one of its metabolic breakdown productsthe smaller fragment Ac-LKKTEwas responsible for the biological activity, suggesting that the entire pharmacological understanding of how TB-500 operates may be flawed or incomplete

The abscissa represents the energy relative to the Fermi level (unit: eV), and the ordinate denotes the DOS (unit: states/eV)

M., Roberts, C