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While research is still limited on the link between vitamin B12 and weight gain, most evidence suggests that the vitamin itself wont cause you to put on pounds, but a deficiency may

Frequency varies depending on your goals and provider recommendations

If youre vegan or mostly plant-based, oral or sublingual B12 is usually enough long term shots are typically for documented deficiency or absorption issues (NIH ODS)

Studies using chondrocyte cell models have investigated whether the GH C-terminal fragment influences cartilage matrix synthesis, chondrocyte proliferation, and growth factor expression in bone and cartilage biology research contexts

A deficiency in this vitamin can lead to serious health problems such as anemia and nerve damage