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Paus R, Arck P, Tiede S

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Mechanisms of Parkinsons disease linked to pathological -Synuclein: new targets for drug discovery

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We observed an increase of pyruvate M + 3 and a decrease in citrate and malate M + 2 isotopologs in bTNF--treated bFLS, suggesting a decreased flow of glucose carbons into the TCA cycle and metabolic rewiring (Fig