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Methodology for assessing vitamin D status has improved significantly in recent years, and the older data reported in many of the studies included in this systematic review may not be accurate or comparable to more current data

Under stress, MOTS-C translocates to the nucleus for direct gene regulation a dual-compartment mechanism unique among metabolic peptides

A study by Huang et al

Diabetes 48(1):7785

Although the equilibrium constant of the reaction favors the formation of SAH, under normal metabolic conditions, low intracellular concentrations of homocysteine and adenosine, SAH formed by transmethylation reactions is hydrolyzed into homocysteine and adenosine (Fig