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Research suggests it may be particularly relevant for visceral fat, making it a potential complementary agent for menopausal weight management

Sorted populations were collected into cooled advanced DMEM/F12, and 5000 live cells were suspended in either Matrigel or collagen matrices and plated as 20 L domes in pre-warmed 24-well plates

First, melatonin appears most useful where oxidative load is high (e.g., PCOS, diminished ovarian reserve, repeat-poor response), aiming to improve oocyte/embryo competence rather than to replace first-line ovulation-induction strategies