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Direct and Metabolite Effects: While direct GLP-1R expression on -cells is low, degradation products of GLP-1, such as GLP-1(9-36) , may also inhibit glucagon secretion by activating inhibitory G proteins (Gi/o) and modulating calcium channels (Zheng et al., 2024)

Our aim was to evaluate A1AT heterozygosity as a risk factor for waitlist mortality, and the potential predictive value of low serum A1AT levels in those with normal phenotype

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