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There is also a critical need for well-designed long-term safety studies addressing the potential side effects of chronic polyphenol supplementation, as current data are mainly limited to short-term animal experiments or isolated compounds, and results from these do not always translate directly to humans (121)

Kariya C, Leitner H, Min E, van Heeckeren C, van Heeckeren A, Day BJ

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The FDA is not required to follow the committees recommendation, but PCAC votes often play an important role in the agencys decision-making process

For instance, epigallocatechin-3-gallate (EGCG), naringenin, resveratrol, and quercetin can prevent breast cancer cells from absorbing and metabolizing glucose (Keating & Martel, 2018)