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Description

Chou, D.A

International journal of radiation oncology, biology, physics

Dysregulated NAD + metabolism accompanies increased glycolytic activity, further accentuated by the upregulation of glucose/lactate transporters and enzymes such as glucose transporter (GLUT)-1/3, MCT1/4 and LDH in response to oncogenic drivers such as HIF-1, PI3K/AKT/mTOR and c-Myc 16