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In each of these 3 studies, the treatment effect, as measured by differences between PROZAC 60 mg and placebo on median reduction from baseline in frequency of bulimic behaviors at endpoint, ranged from 1 to 2 episodes per week for binge-eating and 2 to 4 episodes per week for vomiting

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Available studies have demonstrated that DIS has a protective effect against renal injury induced by diabetic and nephrotoxic drugs, mainly through the regulation of oxidative stress, inflammatory response, lipid metabolism and cellular autophagy (17,2932)

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Lipid profiles (cholesterol and triglycerides) might improve more with dual agonists