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We recently identified the FOXO4 p53 axis as pivotal in maintaining the viability of senescent cells, and that senescent cells can be targeted selectively with the senolytic peptide FOXO4-DRI

Sources Buffoli, B., Rinaldi, F., Labanca, M., Sorbellini, E., Trink, A., Guanziroli, E., Rezzani, R., & Rodella, L

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In simple terms, this means that while both peptides are incredibly good for your brain, they "bias" or lean toward different mechanisms of action