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doi: 10.1016/0092-8674(87)90584-8

This ERK-without-Akt profile supports cellular proliferation and survival while maintaining cells in a proliferative rather than differentiated state contrasting sharply with IGF-1s PI3K/Akt/mTOR-dominant signalling, which drives protein synthesis and differentiation

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Etgen, T., Sander, D., Bickel, H., and Forstl, H

Induction of Wnt/-catenin pathway components, a putative mode of action of NTAPP, was commonly observed in both models, the HF organ culture and in vivo mouse skin