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If intestinal permeability is indeed present in hypertension and involved in its pathophysiological mechanisms, another important question is if BP and its associated end-organ damage could be lowered by a reduction in intestinal permeability

130,131 On the one hand, TMAO is intimately linked to PD risk factors such as metabolic syndrome and cardiovascular disease

Kenny DJ, Plichta DR, Shungin D, Koppel N, Hall AB, Fu B et al (2020) Cholesterol metabolism by uncultured human gut bacteria influences host cholesterol level