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Nuclear receptor and target gene mRNA abundance in duodenum and colon of dogs with chronic enteropathies

ROS measurement The level of ROS in the cells was detected with a MitoSOX Red kit (M36008, Thermo Fisher)

doi: 10.1194/jlr.RA120000628 101 MullenT

Preclinical and clinical evidence indicates that ICIs combined with IL-2 substantially trigger an alternative differentiation pathway in CD8 precursor cells, leading to a transcriptionally and epigenetically distinct effector population with enhanced functionality [234]