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Query: Based on duplex imaging, does the patient have DVT involving (a) right lower extremity only, (b) left lower extremity only, or (c) both lower extremities (bilateral DVT)? Treatments (Clinical) Evidence-based DVT management follows guidelines from the American Society of Hematology (ASH) 2020 VTE Guidelines and the American College of Chest Physicians (ACCP) CHEST Guidelines: Anticoagulation First-Line Treatment DOACs (preferred for most patients): Apixaban 10 mg BID 7 days 5 mg BID

Boon EM, van der Neut R, van de Wetering M, Clevers H, Pals ST

Pain location outside the pelvis can be evaluated by careful history and a body map with pain locations

Hydrogenation was completed using the AutoDock (version 1.5.7), and the molecular docking processes were achieved through AutoDock Vina (version 1.2.5) with the grid boxes parameters (Table S2)

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