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This may be due to the fact that the quercetin binds to either the COVID-19 spike protein at its host receptor region or the spike protein of the human angiotensin-converting enzyme 2 (ACE2) receptor interface, inhibiting the virus entry to cells and disrupting hostvirus interactions indicating its therapeutic potential (Smith and Smith 2020)

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Other studies have demonstrated that MPTP activates the apoptotic cascade by inducing Bax and caspase-3, resulting in caspase-dependent programmed cell death [98, 99]

EV-A71, it is plausible that GSH can still exert a stabilising effect on the capsid, blocking the transition to the altered state (known as A-particle) that is thought to be a precursor to uncoating and infection 25,29

Among other considerations, quantitative aspects are important