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evidence suggests TMAO contributes to OA pathogenesis by promoting chondrocyte apoptosis and ECM degradation (Wang Y

10.1073/pnas.96.24.13703 Proc

As stated earlier in this section, we plan to continue a comprehensive CC/MCC analysis, using a combination of mathematical analysis of claims data and the application of nine guiding principles

The concept was originally defined by Corts-Martn et al

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