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In pathological states where localized or systemic copper excess contributes to hypertrophy, copper chelators can alleviate oxidative stress and subsequent remodeling [12]

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Moreover, a Cochrane review (i.e., pooled analyses of studies with stricter inclusion criteria) of three randomized controlled trials in children with moderate-to-severe asthma (115 children in total) found treatment with intravenous magnesium sulfate on top of standard therapy reduced hospital admission in children with acute asthma by 68% (95% CI, 0.14-0.74) (164)

Alotaibi AS, Yilmaz M, Kanagal-Shamanna R, Loghavi S, Kadia T, DiNardo C, Borthakur G, Pierce S, Wang S, Tang G, Guerra V, Samra B, Pemmaraju N, Jabbour E, Short N, Issa G, Ohanian M, Garcia-Manero G, Bhalla K, Patel K, Takahashi K, Andreeff M , Cortes J, Konopleva M, Ravandi F, Kantarjian H, Daver N

A practical example Suppose you are taking a water pill for blood pressure