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10.2174/092986709788612738 32 FloreanC.SchnekenburgerM.LeeJ

The tumor suppressor YTH domain containing 1 (YTHDC1) participates in the m 6 A methylation of FSP1, leading to reduced stability of FSP1 and increased vulnerability of lung cancer cells to ferroptosis [100]

Future research must integrate multi-omics data to develop individualized therapies, further investigate the stability and plasticity of polarization states, and leverage smart materials and advanced model systems to advance precision immunotherapeutics

Tissue staining Five-micron formalin-fixed, paraffin-embedded tissue sections were used for hematoxylin and eosin (H&E) staining immunohistochemistry and immunofluorescence analyses